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Although recognizing symptoms is important for the initial diagnosis of DSPN, many symptoms in diabetic patients might be caused by something other than DSPN. Subjective symptoms were assessed using 10 question items: Long term clinical effects of epalrestat, an aldose reductase inhibitor, on diabetic peripheral neuropathy:

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A total of Japanese diabetic patients male, female who received a medical interview, physical examination and multiple quantitative nerve function tests were studied. Methods of neurological examination were described previously 6. We believe our data will contribute to devising simple, globally approved diagnostic criteria for DSPN.

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