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Share Tweet Share E-mail Natural-born redheads have a biology unlike any other. The same mutation that makes their hair red is also what causes them to be more sensitive to temperature changes — even slight ones. More sensitive to painkillers The same MC1R mutation that turns their hair red also releases a hormone in the brain that has the ability to mimic endorphins.

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Because the MC1R gene belongs to the same family of genes that play a role in pain, the mutation causes redheads to be more sensitive to it. They also tend to retain their pigment longer and typically have thicker hair than other people.

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